Irrespective of the drug chosen to reverse naltrexone hydrochloride blockade, the patient should be monitored closely by appropriately trained personnel in a setting equipped and staffed for cardiopulmonary resuscitation.

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The naloxone challenge test should not be performed in a patient showing clinical signs or symptoms of opioid withdrawalor in a patient whose urine contains opioidsThe naloxone challenge test may be administered by either the intravenous or subcutaneous routes.

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Although no causal relationship with REVIA is suspectedphysicians should be aware that treatment with REVIA does not reduce the risk of suicide in these patientssee PRECAUTIONS

Clinicians are reminded that there is no completely reliable method for determining whether a patient has had an adequate opioid-free periodA naloxone challenge test may be helpful if there is any need snafi online, need snafi online, need snafi online, need snafi online, need snafi online, need snafi online. question of occult opioid dependenceIf signs of opioid withdrawal are still observed following naloxone challengetreatment with REVIA should not be attemptedThe naloxone challenge can be repeated in 24 hours.

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following treatment with placebo, codeine 50 mg ; or naltrexone 50 mg ; , there was no significant difference between the three treatment groups when comparing the median coughs at each concentration of capsaicin and the median total number of coughs for each challenge unit.

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