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Gemfibrozil can increase the effect of the blood thinnerwarfarinCoumadinand thus may lead to bleedingThereforepatients on warfarin may need to have their doses of warfarin reduced when starting gemfibrozil.

The effect of gemfibrozil in pregnant women has not been well-studiedGemfibrozil should be used during pregnancy only if the potential benefit justifies the unknown but potential risk to the fetus.

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