The pharmacokinetic parameters for danazol after oral administration of 100, 200 and 400 mg single doses to healthy female volunteers are summarized in the following table .
Information about Danazol.
In rare casesdanazol can cause a condition that results in the breakdown of skeletal muscle tissueleading to kidney failureCall your doctor right away if you have unexplained muscle paintendernessor weakness especially if you also have feverunusual tirednessand dark colored urine.
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There is epidemiological and toxicological evidence of hazard in human pregnancyDanazol is known to be associated with the risk of virilisation to the female foetus if administered during human pregnancyDanazol should not be used during pregnancyWomen of childbearing age should be advised to use an effectivenon-hormonalmethod of contraceptionIf the patient conceives during therapyDanazol should be stopped.
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