Side effects due to colchicine appear to be a function of dosage.

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Colchicine comes as a tablet to take by mouth with or without foodWhen colchicine is used to prevent gout attacks or to treat FMFit is usually taken once or twice a dayWhen colchicine is used to relieve the pain of a gout attackone dose is usually taken at the first sign of pain and a secondsmaller dose is usually taken one hour laterIf you do not experience relief or have another attack within buy antibiotics without prescription uk. several days after treatmenttalk to your doctor before taking additional doses of medicationFollow the directions on your prescription label carefullyand ask your doctor or pharmacist to explain any part you do not understandTake colchicine exactly as directedDo not take more or less of it or take it more often than prescribed by your doctor.

Colchicine is a substrate for both CYP3A4 and the transport protein P-gpIn the presence of CYP3A4 or P-gp inhibitorsthe concentrations of colchicine in the blood increaseToxicityincluding fatal caseshave been reported during concurrent use of CYP3A4 or P-gp inhibitors such as macrolidesclarithromycin and erythromycinciclosporinketoconazoleitraconazolevoriconazoleHIV protease inhibitorscalcium channel blockersverapamil and diltiazemand disulfiramsee section 4.4

Before using this medicationtell your doctor or pharmacist your medical historyespecially ofkidney problemsliver problemssuch as cirrhosis

Advise brand cialis and levitra. patients that bone marrow depression with agranulocytosisaplastic anemiaand thrombocytopenia may occur with colchicine capsules.

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