Acarbose precose antibiotics like clarithromycin biaxin , dalfopristin quinupristin synercid , erythromycin e.
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Intestinal adsorbentsfor examplecharcoaland digestive enzyme preparations containing carbohydrate-splitting enzymesfor exampleamylasepancreatinmay reduce the effect of Precose and should not be taken concomitantly.
Jay WMarksMDis a board-certified internist and gastroenterologistHe graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.
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Acarbose is metabolized exclusively within the gastrointestinal tractprincipally by intestinal bacteriabut also by digestive enzymesA fraction of these metabolitesapproximately 34of the dosewas absorbed and subsequently excreted in the urineAt least 13 metabolites have been separated chromatographically from urine specimensThe major metabolites have been identified as 4-methylpyrogallol derivativesthat issulfatemethyland glucuronide conjugatesOne metaboliteformed by cleavage of a glucose molecule from acarbosealso has alpha-glucosidase inhibitory activityThis metabolitetogether with the parent levitra generico en mexico. compoundrecovered from the urineaccounts for less than 2of the total administered dose.
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