Cimetidine tagamet ; clonidine catapres ; digitalis digoxin, lanoxin ; dobutamine dobutrex ; haloperidol haldol ; isoproterenol isuprel ; a blood thinner such as warfarin coumadin, jantoven ; an antidepressant such as amitriptyline elavil, vanatrip, limbitrol , clomipramine anafranil , desipramine norpramin , imipramine janimine, tofranil , and others; an mao inhibitor such as furazolidone furoxone , isocarboxazid marplan , phenelzine nardil , rasagiline azilect , selegiline eldepryl, emsam, zelapar , or tranylcypromine parnate ; aspirin or other nsaids non-steroidal anti-inflammatory drugs such as ibuprofen advil, motrin , naproxen aleve, naprosyn, naprelan, treximet , celecoxib celebrex , diclofenac arthrotec, cambia, cataflam, voltaren, flector patch, pennsaid, solareze , indomethacin indocin , meloxicam mobic , and others; doxazosin cardura , prazosin minipress , terazosin hytrin ; heart or blood pressure medicine such as amlodipine norvasc, caduet, exforge, lotrel, tekamlo, tribenzor, twynsta, amturnide , diltiazem cartia, cardizem , nifedipine nifedical, procardia , reserpine serpasil , verapamil calan, covera, isoptin, verelan , and others; amiodarone cordarone, pacerone , propafenone rythmol , quinidine quin-g ; or an ace inhibitor such as benazepril lotensin , captopril capoten , fosinopril monopril , enalapril vasotec , lisinopril prinivil, zestril , moexipril univasc , perindopril aceon , quinapril accupril , ramipril altace , or trandolapril mavik .

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PharmacokineticsFollowing oral administration of lisinoprilpeak serum concentrations of lisinopril occur within about 7 hoursDeclining serum concentrations exhibit a prolonged terminal phase which does not contribute to drug accumulationThis terminal phase probably represents saturable binding to ACE and is not proportional to doseLisinopril does not bind serum proteins other than ACE.

Use this medication regularly to get the most benefit from itTo help you remembertake it at the same time each dayKeep taking this medication even if you feel wellMost people with high blood pressure do not feel sick.

When lisinopril is given together with thiazide-type diureticsits blood pressure lowering effect is approximately additive.

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