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Taking metoclopramide may cause you to develop a muscle problem called tardive dyskinesiaIf you develop tardive dyskinesiayou will move your musclesespecially the muscles in your face in unusual waysYou will not be able to control or stop these movementsTardive dyskinesia may not go away even after you stop taking metoclopramideThe longer you take metoclopramidethe greater the risk that you will develop tardive dyskinesiaThereforeyour doctor will probably tell you not to take metoclopramide for longer than 12 weeksThe risk that you will develop tardive dyskinesia is also greater if you are taking medications for mental illnessif you have diabetesor if you are elderlyespecially if you are a womanCall your doctor immediately if you develop any uncontrollable body movementsespecially lip smackingmouth puckeringchewingfrowningscowlingsticking out your tongueblinkingeye movementsor shaking arms or legs.
Risk of developing tardive dyskinesia increases with treatment duration and total cumulative dose.
Galactorrheaamenorrheagynecomastiaand impotence reported with prolactin-elevating drugsincluding metoclopramidehyperprolactinemia may potentially stimulate prolactin-dependent breast cancerhoweversome clinical studies and epidemiology studies have not shown an association between administration of dopamine D2 receptor antagonists and tumorigenesis in humans.
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stop giving metoclopramide and contact your veterinarian immediately if your pet has an allergic reaction.