Patients unable to take pyrazinamide or with tuberculosis due to strains of mycobacterium tuberculosis resistant to pyrazinamide should receive isoniazid daily or 5 times week in combination with rifampin and ethambutol for 2 months, then 7 additional months of isoniazid daily, 2 times week, or 5 times week plus rifampin.
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before and during your treatment with isoniazid, pyrazinamide, and rifampin, your doctor may perform tests to make sure your tuberculosis is not resistant to this medicine.
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meperidine major isoniazid, inh has been shown to have some non-selective mao-inhibiting properties.
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peak concentrations of isoniazid in breast milk were 6 micrograms ml after a dose of 5 mg kg and were 16.
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our objective was to describe the pharmacokinetics of rifampin, isoniazid, pyrazinamide, and ethambutol in a cohort of tuberculosis patients established on first-line treatment regimens and to evaluate the determinants of pharmacokinetic variation.
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